Feasibility of pulse rate variability as feedback in closed-loop percutaneous auricular vagus nerve stimulation
نویسندگان
چکیده
منابع مشابه
Extracellular pH monitoring for use in closed-loop vagus nerve stimulation.
OBJECTIVE Vagal nerve stimulation (VNS) has shown potential benefits for obesity treatment; however, current devices lack physiological feedback, which limit their efficacy. Changes in extracellular pH (pHe) have shown to be correlated with neural activity, but have traditionally been measured with glass microelectrodes, which limit their in vivo applicability. APPROACH Iridium oxide has prev...
متن کاملA novel controller based on state-transition models for closed-loop vagus nerve stimulation: Application to heart rate regulation
Vagus nerve stimulation (VNS) is an established adjunctive therapy for pharmacologically refractory epilepsy and depression and is currently in active clinical research for other applications. In current clinical studies, VNS is delivered in an open-loop approach, where VNS parameters are defined during a manual titration phase. However, the physiological response to a given VNS configuration s...
متن کاملEffects of short and prolonged transcutaneous vagus nerve stimulation on heart rate variability in healthy subjects.
The vagus nerve is strategically located in the body, and has multiple homeostatic and health-promoting effects. Low vagal activity predicts onset and progression of diseases. These are the reasons to activate this nerve. This study examined the effects of transcutaneous vagus nerve stimulation (t-VNS) on a main index of vagal activity, namely heart rate variability (HRV). In Study 1, we compar...
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Primary cervical dystonia is characterized by abnormal, involuntary, and sustained contractions of cervical muscles. Current ways of treatment focus on alleviating symptomatic muscle activity. Besides pharmacological treatment, in severe cases patients may receive neuromodulative intervention such as deep brain stimulation. However, these (highly invasive) methods have some major drawbacks. For...
متن کاملVagus nerve stimulation improves severely impaired heart rate variability in a patient with Lennox-Gastaut-Syndrome
Vagus nerve stimulation (VNS) is a new therapeutic option for refractory epilepsy. We report a patient with Lennox-Gastaut-Syndrome (LGS) and a severe impairment of heart rate variability (HRV), we could demonstrate in our patient that HRV was improved by VNS.
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ژورنال
عنوان ژورنال: Vibroengineering PROCEDIA
سال: 2019
ISSN: 2345-0533,2538-8479
DOI: 10.21595/vp.2019.20949